Description

Quinoline, 7-Bromo-4-[5,6-Dihydro-2-(6-Methyl-2-Pyridinyl)-4H-Pyrrolo[1,2-B]Pyrazol-3-Yl]- is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for medicinal chemistry research and development, offering a sophisticated heterocyclic scaffold for targeted drug discovery. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Serves as a precursor for developing molecular probes to study biological pathways and protein interactions.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct complex heterocyclic systems with specific pharmacological properties.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for the cGMP production of clinical trial materials and commercial APIs.

Basic Information

Product Name	Quinoline, 7-Bromo-4-[5,6-Dihydro-2-(6-Methyl-2-Pyridinyl)-4H-Pyrrolo[1,2-B]Pyrazol-3-Yl]-
CAS No.	476474-61-0
Molecular Formula	C20H17BrN4
Molecular Weight	393.28 g/mol
Synonyms	7-Bromo-4-(5,6-dihydro-2-(6-methylpyridin-2-yl)-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline; 7-Bromo-4-[2-(6-methyl-2-pyridinyl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline; 476474-61-0; Quinoline, 7-bromo-4-[5,6-dihydro-2-(6-methyl-2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]-; BDBM50164957; AKOS025247213; ZINC000253909793; A1-00874
EINECS	Contact for details

Quality Control

Our Quinoline, 7-Bromo-4-[5,6-Dihydro-2-(6-Methyl-2-Pyridinyl)-4H-Pyrrolo[1,2-B]Pyrazol-3-Yl]- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all critical quality attributes. We support development and commercial projects with material suitable for research use, preclinical studies, and cGMP manufacturing upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.