Description

(R)-Borohomophe-(+)-Pinanediol-Hcl is a high-purity, chiral organoboron reagent used as a key intermediate in advanced synthetic chemistry. Its value lies in providing a stereochemically defined boronic ester functionality, which is crucial for constructing complex molecules with high enantiomeric purity. This product is essential for researchers and process chemists in the pharmaceutical and fine chemical industries, particularly for applications in asymmetric synthesis, cross-coupling reactions, and the development of active pharmaceutical ingredients (APIs).

Application

• Asymmetric Synthesis: As a chiral building block for the stereoselective construction of carbon-carbon and carbon-heteroatom bonds.
• Pharmaceutical Intermediates: A critical precursor in the synthesis of enantiomerically pure drug candidates and active pharmaceutical ingredients (APIs).
• Suzuki-Miyaura Cross-Coupling: Serves as a chiral organoboron reagent in palladium-catalyzed cross-coupling reactions to introduce specific stereocenters.
• Catalyst and Ligand Development: Used in the research and production of novel chiral catalysts and ligands for homogeneous catalysis.
• Fine Chemical Production: Employed in the manufacture of high-value, complex specialty chemicals where precise stereochemistry is required.
• Academic and R&D Laboratories: A valuable tool for methodological development in organic synthesis and medicinal chemistry research.

Basic Information

Product Name	(R)-Borohomophe-(+)-Pinanediol-Hcl
CAS No.	476334-33-5
Molecular Formula	C₁₇H₂₄BClO₂
Molecular Weight	306.63 g/mol
Synonyms	(R)-2-(2-Boronoethyl)benzenaminium chloride, (1R)-(-)-Pinanediol ester; (R)-Borohomophenylalanine Pinanediol Ester Hydrochloride; (R)-α-Amino boronic acid homophenylalanine pinanediol ester HCl; (R)-HomoPhe(Bpin)-OH•HCl pinanediol ester; Borono-L-homophenylalanine pinanediol ester hydrochloride; (R)-2-Amino-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butanoic acid pinanediol ester hydrochloride; Boro-L-homophe(pin)-OH•HCl
EINECS	Contact for details

Quality Control

Every batch of (R)-Borohomophe-(+)-Pinanediol-Hcl is produced under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with high-purity standards typical for advanced pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming key parameters such as chiral purity, chemical purity, and identity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. For long-term storage, consider storing at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.