Description

4-Hydroxybenzo[B]Thiophene-2-Carbonitrile is a high-purity, light-sensitive organic intermediate of significant value in advanced chemical synthesis. This compound matters for its role as a versatile building block in the development of complex heterocyclic molecules, particularly within the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, leveraging the bioactivity of the benzothiophene core.
• Material Science Research: Serves as a building block for organic semiconductors, liquid crystals, and other functional organic materials due to its electron-deficient nitrile group.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments where the hydroxyl and nitrile functionalities allow for color tuning and polymer attachment.
• Chemical Biology Probe Development: Utilized as a scaffold for creating molecular probes and inhibitors to study enzyme function and biological pathways.

Basic Information

Product Name	4-Hydroxybenzo[B]Thiophene-2-Carbonitrile
CAS No.	476199-30-1
Molecular Formula	C9H5NOS
Molecular Weight	175.21 g/mol
Synonyms	4-Hydroxybenzo[b]thiophene-2-carbonitrile; 4-Hydroxy-1-benzothiophene-2-carbonitrile; 2-Cyano-4-hydroxybenzo[b]thiophene; 4-Hydroxy-2-cyanobenzo[b]thiophene; Benzo[b]thiophene-2-carbonitrile, 4-hydroxy-; 476199-30-1; 4-Hydroxybenzo(b)thiophene-2-carbonitrile
EINECS	Contact for details

Quality Control

Our 4-Hydroxybenzo[B]Thiophene-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging are performed under controlled lighting conditions.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.