Description

2-Bromo-6-Methoxyquinoline is a versatile halogenated quinoline derivative that serves as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in its reactive bromine substituent and methoxy group, which enable precise functionalization for constructing complex molecular architectures. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for developing active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in the development of kinase inhibitors, antimicrobial agents, and other biologically active quinoline-based compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides where the quinoline scaffold imparts specific biological activity.
• Material Science Research: Serves as a building block for creating organic electronic materials, ligands for catalysis, and functional dyes due to its conjugated aromatic system.
• Chemical Research & Development: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and other metal-catalyzed transformations to create complex chemical libraries.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized nitrogen-containing ligands used in homogeneous catalysis.

Basic Information

Product Name	2-Bromo-6-Methoxyquinoline
CAS No.	476161-59-8
Molecular Formula	C₁₀H₈BrNO
Molecular Weight	238.08 g/mol
Synonyms	6-Methoxy-2-bromoquinoline; 2-Bromo-6-methoxyquinoline; Quinoline, 2-bromo-6-methoxy-; 2-Brom-6-methoxychinolin (German); 2-ブロモ-6-メトキシキノリン (Japanese)
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Methoxyquinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to verify identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality parameters. We support cGMP and ISO standards for pharmaceutical and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.