Description

1-Bromo-2,3-Dihydro-6-Methoxy-1H-Indene is a specialized brominated indane derivative, serving as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in its unique molecular scaffold, which provides a versatile platform for constructing complex heterocyclic and pharmaceutical compounds. This high-purity building block is essential for researchers and manufacturers in pharmaceutical development, agrochemical synthesis, and materials science who require reliable, high-quality intermediates for their R&D and production processes.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its bromine moiety for further functionalization.
• Material Science Research: Serves as a precursor for organic electronic materials, such as charge-transport molecules or ligands for metal-organic frameworks (MOFs).
• Chemical Biology: Employed as a probe or linker in medicinal chemistry for structure-activity relationship (SAR) studies and bioconjugation.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis, including cross-coupling reactions and ring-forming transformations.

Basic Information

Product Name	1-Bromo-2,3-Dihydro-6-Methoxy-1H-Indene
CAS No.	475475-77-5
Molecular Formula	C₁₀H₁₁BrO
Molecular Weight	227.10 g/mol
Synonyms	1-Bromo-6-methoxy-2,3-dihydro-1H-indene; 6-Methoxy-2,3-dihydro-1H-inden-1-yl bromide; 1-Bromo-6-methoxyindane; 1-Bromo-2,3-dihydro-6-methoxyindene; 475475-77-5; 1H-Indene, 1-bromo-2,3-dihydro-6-methoxy-
EINECS	Contact for details

Quality Control

Our 1-Bromo-2,3-Dihydro-6-Methoxy-1H-Indene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing identity, purity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.