Description

1-Naphthalenol, 1,2,3,4-Tetrahydro-, Monohydrate, (1R)- (9Ci) is a chiral, tetrahydro-naphthol derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and stereochemically defined building block for constructing complex molecular architectures, particularly in the pharmaceutical sector. It is needed by research chemists and process development teams in the fine chemical and pharmaceutical industries for applications such as asymmetric synthesis and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Utilized as a building block in stereoselective reactions to introduce the (1R)-tetrahydronaphthol moiety into target molecules.
• Ligand and Catalyst Development: Serves as a precursor for the synthesis of chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals for agrochemical, fragrance, and material science applications.
• Academic and Industrial Research: Used in methodological studies and process chemistry research to explore new synthetic pathways.

Basic Information

Product Name	1-Naphthalenol, 1,2,3,4-Tetrahydro-, Monohydrate, (1R)- (9Ci)
CAS No.	474658-78-1
Molecular Formula	C₁₀H₁₂O • H₂O
Molecular Weight	166.22 g/mol (Anhydrous basis: 148.20 g/mol)
Synonyms	(1R)-1,2,3,4-Tetrahydro-1-naphthol Monohydrate; (R)-1,2,3,4-Tetrahydro-1-naphthol Hydrate; (R)-1,2,3,4-Tetrahydro-1-naphthalenol Monohydrate; (R)-α-Tetralol Monohydrate; (1R)-1-Hydroxy-1,2,3,4-tetrahydronaphthalene Hydrate; (R)-1-Tetralol Monohydrate; (R)-1,2,3,4-Tetrahydro-1-hydroxy-naphthalene Hydrate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide Certificates of Analysis (COA) for every batch, detailing key parameters such as chiral purity, chemical assay, and impurity profiles. Quality is assured through analytical techniques including HPLC, GC, and chiral analysis. Specifications can be developed to meet specific cGMP or research-grade requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	Theoretical (Monohydrate)
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.