Description

Boc-6-Amino-1,2,3,4-Tetrahydroquinoline is a protected amine derivative of the tetrahydroquinoline scaffold, serving as a crucial high-purity building block in advanced organic synthesis. Its primary value lies in providing a reactive amino group that is shielded by the acid-labile tert-butoxycarbonyl (Boc) protecting group, enabling selective deprotection during multi-step synthetic sequences. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries who are developing novel active compounds and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Building block for developing novel pesticides and herbicides with enhanced efficacy and selectivity.
• Organic Synthesis: Versatile scaffold for constructing complex heterocyclic compounds and natural product analogs in medicinal chemistry.
• Material Science: Monomer or functional unit for creating advanced polymers, dyes, and photoactive materials.
• Chemical Biology: Used in the preparation of molecular probes and bioconjugates for studying biological pathways.
• Academic & R&D: Fundamental research reagent for methodological development and exploring new chemical spaces.

Basic Information

Product Name	Boc-6-Amino-1,2,3,4-Tetrahydroquinoline
CAS No.	474539-25-8
Molecular Formula	C14H20N2O2
Molecular Weight	248.32 g/mol
Synonyms	1,2,3,4-Tetrahydro-6-quinolinamine, N-Boc derivative; tert-Butyl (1,2,3,4-tetrahydroquinolin-6-yl)carbamate; 6-[(tert-Butoxycarbonyl)amino]-1,2,3,4-tetrahydroquinoline; N-Boc-6-Aminotetrahydroquinoline; Boc-6-ATQ; 6-Amino-1,2,3,4-tetrahydroquinoline N-Boc protected; N-(tert-Butoxycarbonyl)-1,2,3,4-tetrahydroquinolin-6-amine
EINECS	Contact for details

Quality Control

Our Boc-6-Amino-1,2,3,4-Tetrahydroquinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment. We support compliance with REACH, TSCA, and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.