Description

(Rs)-1-[2-(Trifluoromethyl)Phenyl]Propylamine is a chiral amine building block featuring a trifluoromethylphenyl group, offering unique steric and electronic properties for advanced synthesis. This compound is critical for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and agrochemicals, where its structural motif can enhance metabolic stability and binding affinity. It is primarily needed by the pharmaceutical, agrochemical, and specialty chemical industries for applications in asymmetric synthesis and as a key intermediate in the creation of bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly in central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the trifluoromethyl group contributes to efficacy and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric hydrogenation and carbon-carbon bond formation reactions.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with tailored electronic properties.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes to study enzyme function and biological pathways.

Basic Information

Product Name	(Rs)-1-[2-(Trifluoromethyl)Phenyl]Propylamine
CAS No.	473732-54-6
Molecular Formula	C10H12F3N
Molecular Weight	203.20 g/mol
Synonyms	(R)-1-[2-(Trifluoromethyl)phenyl]propan-1-amine; (R)-α-Methyl-2-(trifluoromethyl)benzeneethanamine; (R)-1-(2-Trifluoromethylphenyl)propylamine; (R)-2-(Trifluoromethyl)benzenepropanamine; (R)-1-Amino-1-(2-trifluoromethylphenyl)propane; (R)-1-(α,α,α-Trifluoro-o-tolyl)propylamine; (R)-1-(2-(Trifluoromethyl)phenyl)propan-1-amine; (R)-1-(2-Trifluoromethylphenyl)-1-aminopropane
EINECS	Contact for details

Quality Control

Our (Rs)-1-[2-(Trifluoromethyl)Phenyl]Propylamine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.