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tert-Butyl (5-Chloro-4-Fluoro-2-Nitrophenyl)Carbamate CAS NO 473547-10-3


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CAS No.:473547-10-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

tert-Butyl (5-Chloro-4-Fluoro-2-Nitrophenyl)Carbamate is a high-purity, advanced pharmaceutical intermediate (API) characterized by its halogenated aromatic structure. This compound is critical for the synthesis of complex active molecules, offering a protected amine group for controlled, multi-step organic reactions. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel therapeutic and crop protection agents.

Application

  • Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders and oncology.
  • Agrochemical Research: Serves as a precursor in the development of new herbicides and pesticides, leveraging its halogenated nitroaromatic core.
  • Organic Synthesis: Used in academic and industrial R&D for constructing complex heterocyclic compounds and fine chemicals.
  • Material Science: Potential monomer or precursor for specialty polymers and advanced functional materials.
  • Chemical Biology: Employed in the synthesis of probes and ligands for biochemical and pharmacological studies.

Basic Information

Product Name tert-Butyl (5-Chloro-4-Fluoro-2-Nitrophenyl)Carbamate
CAS No. 473547-10-3
Molecular Formula C11H12ClFN2O4
Molecular Weight 290.68 g/mol
Synonyms Boc-5-Chloro-4-Fluoro-2-Nitroaniline; tert-Butyl N-(5-Chloro-4-Fluoro-2-Nitrophenyl)Carbamate; 1,1-Dimethylethyl N-(5-Chloro-4-Fluoro-2-Nitrophenyl)Carbamate; 5-Chloro-4-Fluoro-2-Nitroaniline N-Boc Derivative; 2-Nitro-5-Chloro-4-Fluoroaniline Boc Protected; Boc-Protected 5-Chloro-4-Fluoro-2-Nitroaniline; (5-Chloro-4-Fluoro-2-Nitrophenyl)Carbamic Acid tert-Butyl Ester
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Quality Control

Our tert-Butyl (5-Chloro-4-Fluoro-2-Nitrophenyl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to guarantee batch-to-batch consistency and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. The container should be kept tightly sealed when not in use to prevent degradation.

Specification

Item Specification
Appearance Off-white to light yellow crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0%
Single Maximum Impurity ≤ 0.5%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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