Description

5-Chloro-4-Iodo-2-Methoxybenzoic Acid is a high-purity, multi-functional halogenated benzoic acid derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique substitution pattern makes it a valuable scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated aromatic motifs into their target structures.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators that require halogenated aromatic cores.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and polymers where halogen and methoxy functionalities are desired.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A versatile starting material for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	5-Chloro-4-Iodo-2-Methoxybenzoic Acid
CAS No.	473264-13-0
Molecular Formula	C8H6ClIO3
Molecular Weight	312.49 g/mol
Synonyms	2-Methoxy-5-chloro-4-iodobenzoic acid; 4-Iodo-5-chloro-2-methoxybenzoic acid; Benzoic acid, 5-chloro-4-iodo-2-methoxy-; 5-Chloro-4-iodo-o-anisic acid; 5-Chloro-4-iodo-2-methoxybenzoic acid; 473264-13-0; 5-Chloro-4-iodo-2-methoxy-benzoic acid
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-4-Iodo-2-Methoxybenzoic Acid is produced and tested under strict quality management protocols to ensure consistency and reliability for your critical applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, and we support customer audits and regulatory documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and stored away from direct light and moisture to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.