Description

Di-(2-Pyridyl)(Dicyclohexylphosphino)Amine is a specialized, high-purity organophosphorus ligand with the CAS number 472959-98-1. This compound is valued for its strong electron-donating properties and steric bulk, making it a critical component in advanced catalytic systems. It is primarily sought by researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing and scaling up complex cross-coupling and hydrogenation reactions.

Application

• As a ligand in homogeneous catalysis for C-C and C-N cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
• Key component in catalyst systems for asymmetric hydrogenation of olefins and ketones in pharmaceutical intermediate synthesis.
• Used in the development of novel metal-organic frameworks (MOFs) and coordination polymers for material science.
• Employed in academic and industrial R&D for studying structure-activity relationships in organometallic chemistry.
• Facilitates chiral synthesis in the production of active pharmaceutical ingredients (APIs) and agrochemicals.
• Applied in polymerization catalysis for creating specialty polymers with controlled architectures.

Basic Information

Product Name	Di-(2-Pyridyl)(Dicyclohexylphosphino)Amine
CAS No.	472959-98-1
Molecular Formula	C22H32N3P
Molecular Weight	369.49 g/mol
Synonyms	Di(2-pyridyl)(dicyclohexylphosphino)amine; DPPA; (Dicyclohexylphosphino)bis(2-pyridyl)amine; N-(Dicyclohexylphosphino)-2,2'-dipyridylamine; N-(Dicyclohexylphosphanyl)di(pyridin-2-yl)amine; Di-2-pyridyl(dicyclohexylphosphino)amine; 2,2'-Dipyridylamine, N-(dicyclohexylphosphino)-
EINECS	Contact for details

Quality Control

Our Di-(2-Pyridyl)(Dicyclohexylphosphino)Amine is manufactured under strict quality protocols to ensure batch-to-batch consistency and high performance in sensitive catalytic applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality system is designed to meet the stringent requirements of pharmaceutical and advanced material research.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This material is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air and moisture must be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.