Description

2,3-Di-o-Benzyl-4,6-o-Ethylidene-D-Glucopyranose is a key protected carbohydrate intermediate, specifically a benzylidene acetal derivative of D-glucose. This compound is critical for synthetic chemists as it provides selective protection of hydroxyl groups, enabling complex multi-step synthesis with high regiochemical control. It is primarily utilized in the research and development of pharmaceuticals, agrochemicals, and novel chiral materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly for nucleoside analogs and glycosidase inhibitors.
• Glycosylation Reactions: Serves as a glycosyl donor or acceptor in the stereoselective construction of oligosaccharides and glycoconjugates.
• Chiral Pool Synthesis: Used as a starting material from the chiral pool for the preparation of enantiomerically pure natural products and fine chemicals.
• Agrochemical Research: Employed in developing novel, biologically active compounds with specific stereochemical configurations.
• Material Science: Acts as a precursor for chiral ligands, catalysts, and functional polymers requiring specific sugar-based architectures.

Basic Information

Product Name	2,3-Di-o-Benzyl-4,6-o-Ethylidene-D-Glucopyranose
CAS No.	471863-88-4
Molecular Formula	C22H26O6
Molecular Weight	386.44 g/mol
Synonyms	1,2-Di-O-benzyl-4,6-O-ethylidene-D-glucopyranose; 4,6-O-Ethylidene-2,3-di-O-benzyl-D-glucopyranose; D-Glucopyranose, 2,3-bis-O-(phenylmethyl)-4,6-O-ethylidene-; 2,3-Di-O-benzyl-4,6-O-ethylidene-D-glucose; Benzylidene Acetal Protected D-Glucose Derivative
EINECS	Contact for details

Quality Control

Our 2,3-Di-o-Benzyl-4,6-o-Ethylidene-D-Glucopyranose is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation [α]²⁰D	Contact for details
Melting Point	Contact for details
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.