Description

(2S,4S)-2,4-Dimethylazetidine Hydrochloride CAS NO 470666-35-4 is a high-purity, chiral azetidine derivative supplied as a hydrochloride salt. This compound serves as a critical chiral building block and intermediate in the synthesis of complex pharmaceutical molecules, particularly in the development of active pharmaceutical ingredients (APIs). It is essential for research and production in medicinal chemistry, where its defined stereochemistry enables the creation of enantiomerically pure compounds. Key industries that rely on this material include pharmaceutical R&D, contract manufacturing organizations (CMOs), and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, especially in central nervous system (CNS) and metabolic disease research.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• API Development: Integrated into the synthetic route of advanced pharmaceutical intermediates and final active pharmaceutical ingredients.
• Chemical Biology Probes: Used in the development of molecular probes to study biological pathways and enzyme functions.
• Fine Chemical Synthesis: Serves as a building block for the preparation of other specialty chemicals and complex organic molecules.

Basic Information

Product Name	(2S,4S)-2,4-Dimethylazetidine Hydrochloride
CAS No.	470666-35-4
Molecular Formula	C5H12ClN
Molecular Weight	121.61 g/mol
Synonyms	(2S,4S)-2,4-Dimethylazetidine HCl; (2S,4S)-2,4-Dimethylazetidine Hydrochloride; (2S,4S)-2,4-Dimethylazetidinium Chloride; (2S,4S)-2,4-Dimethyl-1-azetidine Hydrochloride; (2S,4S)-2,4-Dimethylazacyclobutane Hydrochloride; (2S,4S)-2,4-Dimethylazetidine Monohydrochloride; Azetidine, 2,4-dimethyl-, hydrochloride, (2S,4S)-; 470666-35-4
EINECS	Contact for details

Quality Control

Our (2S,4S)-2,4-Dimethylazetidine Hydrochloride is manufactured under strict quality control protocols to ensure high chemical purity and chiral integrity, suitable for demanding pharmaceutical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of global pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.