Description

2-Azabicyclo[2.2.0]Hex-5-En-3-One,2-(2-Methylpropyl)-,(+)-(9Ci) is a high-value, chiral bicyclic lactam building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily needed by research institutions and industrial R&D departments focused on medicinal chemistry, process development, and the synthesis of enantiomerically pure compounds.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in classes requiring constrained, nitrogen-containing bicyclic scaffolds.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new bioactive molecules.
• Agrochemical Synthesis: Serves as a building block for developing new, enantiomerically pure pesticides and herbicides with improved efficacy.
• Asymmetric Catalysis: Employed as a substrate or ligand precursor in the development and testing of new asymmetric catalytic reactions.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and for creating compound libraries for high-throughput screening.

Basic Information

Product Name	2-Azabicyclo[2.2.0]Hex-5-En-3-One,2-(2-Methylpropyl)-,(+)-(9Ci)
CAS No.	470661-07-5
Molecular Formula	C9H13NO
Molecular Weight	151.21 g/mol
Synonyms	(+)-2-(2-Methylpropyl)-2-azabicyclo[2.2.0]hex-5-en-3-one; 2-Isobutyl-2-azabicyclo[2.2.0]hex-5-en-3-one, (+)-; 2-Azabicyclo[2.2.0]hex-5-en-3-one, 2-(2-methylpropyl)-, (1R,4S,5R)-; (1R,4S,5R)-2-(2-Methylpropyl)-2-azabicyclo[2.2.0]hex-5-en-3-one; Bicyclic β-lactam intermediate; Chiral bicyclic lactam
EINECS	Contact for details

Quality Control

Our 2-Azabicyclo[2.2.0]Hex-5-En-3-One,2-(2-Methylpropyl)-,(+)-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep the container in a cool, dry place at temperatures between 2°C and 8°C (refrigerated). The compound may be moisture-sensitive; ensure the container is sealed under an inert atmosphere such as nitrogen or argon to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.