Description

2-Azabicyclo[2.2.0]Hex-5-En-3-One,2-Propyl-,(-)-(9Ci) is a high-purity, chiral bicyclic lactam building block of significant interest in advanced organic synthesis. Its unique, constrained molecular framework makes it a valuable precursor for constructing complex nitrogen-containing heterocycles and pharmacologically active scaffolds. This compound is primarily utilized by pharmaceutical R&D organizations and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Asymmetric Synthesis: Employed as a building block in stereoselective reactions to introduce complex, three-dimensional molecular architecture.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-donor ligands used in transition metal catalysis.
• Agrochemical Research: Used in the synthesis of novel herbicides and pesticides with specific chiral activity.
• Academic & Institutional Research: A valuable tool for methodological studies in organic chemistry and heterocyclic chemistry.
• Fine Chemical Production: Integrated into multi-step synthesis processes for high-value specialty chemicals.

Basic Information

Product Name	2-Azabicyclo[2.2.0]Hex-5-En-3-One,2-Propyl-,(-)-(9Ci)
CAS No.	470661-03-1
Molecular Formula	C8H11NO
Molecular Weight	137.18 g/mol
Synonyms	(-)-2-Propyl-2-azabicyclo[2.2.0]hex-5-en-3-one; (1S,4R,5R)-2-Propyl-2-azabicyclo[2.2.0]hex-5-en-3-one; 2-Propyl-2-azabicyclo[2.2.0]hex-5-en-3-one, (-)-; 2-Azabicyclo[2.2.0]hex-5-en-3-one, 2-propyl-, (-)-; Bicyclic lactam derivative; Chiral bicyclic lactam; 470661-03-1
EINECS	Contact for details

Quality Control

Our 2-Azabicyclo[2.2.0]Hex-5-En-3-One,2-Propyl-,(-)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure consistent high quality and chemical identity. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.