Description

4-(Trifluoromethoxy)-Benzenepropanamine is a high-purity aromatic amine derivative featuring a trifluoromethoxy substituent. This compound is a critical pharmaceutical intermediate valued for its role in modulating the pharmacokinetic and physicochemical properties of active pharmaceutical ingredients (APIs). It is primarily utilized by research organizations and fine chemical manufacturers engaged in the development of novel therapeutics, agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethoxy group enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with unique electronic properties.
• Life Science Research: Utilized as a biochemical tool compound in medicinal chemistry programs for structure-activity relationship (SAR) studies.

Basic Information

Product Name	4-(Trifluoromethoxy)-Benzenepropanamine
CAS No.	465529-50-4
Molecular Formula	C10H12F3NO
Molecular Weight	219.20 g/mol
Synonyms	3-[4-(Trifluoromethoxy)phenyl]propan-1-amine; 4-(Trifluoromethoxy)phenethylamine; 1-Amino-3-[4-(trifluoromethoxy)phenyl]propane; Benzenepropanamine, 4-(trifluoromethoxy)-; 4-Trifluoromethoxyphenpropylamine; γ-(4-Trifluoromethoxyphenyl)propylamine
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethoxy)-Benzenepropanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profile, and physical characteristics are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.