Description

2,4-Dichloro-6-Hydroxyquinazoline is a versatile and high-value halogenated quinazoline derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring reactive chloro and hydroxy substituents, makes it an essential building block for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors, anticancer agents, and other biologically active quinazoline-based compounds.
• Agrochemical Research: Building block for developing new herbicides, fungicides, and plant growth regulators with optimized efficacy.
• Material Science: Used in the research and development of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for optoelectronic devices.
• Chemical Synthesis: Serves as a versatile scaffold for further functionalization via nucleophilic aromatic substitution and other coupling reactions in custom synthesis and process development.
• Academic & R&D: Fundamental reagent in university and corporate research laboratories for exploring new chemical reactions and synthesizing novel heterocyclic libraries for screening.

Basic Information

Product Name	2,4-Dichloro-6-Hydroxyquinazoline
CAS No.	464927-05-7
Molecular Formula	C8H4Cl2N2O
Molecular Weight	215.04 g/mol
Synonyms	6-Hydroxy-2,4-dichloroquinazoline; 2,4-Dichloro-6-quinazolinol; 2,4-Dichloro-6-hydroxy-1,3-diazanaphthalene; Quinazoline, 2,4-dichloro-6-hydroxy-; AOB 67734; ZINC000003869756; BDBM50111657; AKOS005209156
EINECS	Contact for details

Quality Control

Every batch of 2,4-Dichloro-6-Hydroxyquinazoline is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.