Description

(2S,3R)-3-([(3-Methoxyphenyl)Amino]Carbonyl)Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid CAS NO 464877-92-7 is a high-purity, chiral bicyclic compound featuring a carboxylic acid and a substituted anilide functional group. This specific stereochemistry makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily sought after by pharmaceutical R&D and fine chemical synthesis teams for developing novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key chiral building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) or anti-inflammatory targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis due to its rigid bicyclic core and multiple functional handles.
• Asymmetric Synthesis: Serves as a precursor or template in catalytic asymmetric reactions to create other enantiomerically pure compounds.
• Protease Inhibitor Development: The carboxylic acid and amide motifs make it a candidate scaffold for designing enzyme inhibitors.
• Ligand Synthesis: Can be utilized to create complex ligands for catalysis or metal-organic frameworks (MOFs).
• Academic & Institutional Research: Employed in chemical biology and organic methodology development projects.

Basic Information

Product Name	(2S,3R)-3-([(3-Methoxyphenyl)Amino]Carbonyl)Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid
CAS No.	464877-92-7
Molecular Formula	C17H19NO4
Molecular Weight	301.34 g/mol
Synonyms	(1S,2R,3S,4R)-3-[(3-Methoxyphenyl)carbamoyl]bicyclo[2.2.1]hept-5-ene-2-carboxylic acid; (2S,3R)-3-[(3-Methoxybenzoyl)amino]bicyclo[2.2.1]hept-5-ene-2-carboxylic acid; endo-(1S,2R,3S,4R)-3-(3-Methoxybenzamido)bicyclo[2.2.1]hept-5-ene-2-carboxylic Acid; Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, 3-[[(3-methoxyphenyl)amino]carbonyl]-, (1S,2R,3S,4R)-; 464877-92-7; (1S,2R,3S,4R)-3-(3-Methoxybenzamido)bicyclo[2.2.1]hept-5-ene-2-carboxylic Acid
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; therefore, containers should be kept tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.