Description

1-Propanone,1-(1R,2S,4R)-Bicyclo[2.2.1]Hept-5-En-2-Yl-(9Ci) is a high-purity chiral building block and advanced pharmaceutical intermediate characterized by its bicyclic norbornene-derived structure. This compound is critical for the synthesis of complex molecules where stereochemical control is paramount, offering a defined three-dimensional scaffold for medicinal chemistry and asymmetric synthesis. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Asymmetric Catalysis: Used as a ligand precursor or a chiral auxiliary in catalytic reactions to induce enantioselectivity.
• Agrochemical Synthesis: Employed in the production of advanced, stereochemically-defined pesticides and herbicides.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialized polymers with unique thermal or mechanical properties.
• Flavor & Fragrance Chemistry: Utilized in the synthesis of complex, high-value aroma chemicals where specific stereoisomers are required for olfactory profile.
• Academic & Process Chemistry: A valuable reagent for methodological studies in organic synthesis and scale-up process optimization.

Basic Information

Product Name	1-Propanone,1-(1R,2S,4R)-Bicyclo[2.2.1]Hept-5-En-2-Yl-(9Ci)
CAS No.	463941-19-7
Molecular Formula	C10H14O
Molecular Weight	150.22 g/mol
Synonyms	1-[(1R,2S,4R)-Bicyclo[2.2.1]hept-5-en-2-yl]propan-1-one; (1R,2S,4R)-2-Propionylbicyclo[2.2.1]hept-5-ene; (1R,2S,4R)-Norborn-5-ene-2-yl ethyl ketone; endo-2-Propionyl-5-norbornene; Chiral Norbornenyl Ethyl Ketone; (1R,2S,4R)-5-Norbornene-2-ethyl ketone; Bicyclo[2.2.1]hept-5-ene-2-propanone, (1R,2S,4R)-
EINECS	Contact for details

Quality Control

Our production of 1-Propanone,1-(1R,2S,4R)-Bicyclo[2.2.1]Hept-5-En-2-Yl-(9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and consistency for your critical R&D and manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.