Description

2-(5-Methyl-4H-[1,2,4]Triazol-3-Yl)-Ethylamine Dihydrochloride is a high-purity, pharmaceutically relevant organic salt, primarily utilized as a critical synthetic intermediate. Its value lies in providing a functionalized triazole-ethylamine backbone, essential for constructing complex molecules in drug discovery and development. This compound is specifically needed by research institutions and pharmaceutical companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological and oncological pathways.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those containing triazole heterocycles.
• Bioconjugation & Probe Development: The amine functionality allows for conjugation to fluorescent dyes, biotin, or other molecules for creating biochemical probes.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Ligand Synthesis: Serves as a precursor for creating chelating ligands in coordination chemistry and catalyst design.
• Peptidomimetics: Incorporated into peptide analogs to enhance metabolic stability or modify biological activity.
• Agrochemical Research: Potential intermediate in the development of new fungicides or plant growth regulators.

Basic Information

Product Name	2-(5-Methyl-4H-[1,2,4]Triazol-3-Yl)-Ethylamine Dihydrochloride
CAS No.	462651-77-0
Molecular Formula	C5H11N5 · 2HCl
Molecular Weight	226.10 g/mol (free base: 153.18 g/mol)
Synonyms	5-Methyl-1H-1,2,4-triazol-3-ylethanamine dihydrochloride; 2-(5-Methyl-1H-1,2,4-triazol-3-yl)ethan-1-amine dihydrochloride; 3-(2-Aminoethyl)-5-methyl-1H-1,2,4-triazole dihydrochloride; 5-Methyl-3-(2-aminoethyl)-1,2,4-triazole dihydrochloride; 2-(5-Methyl-4H-1,2,4-triazol-3-yl)ethylamine hydrochloride (1:2); 462651-77-0
EINECS	Contact for details

Quality Control

Our 2-(5-Methyl-4H-[1,2,4]Triazol-3-Yl)-Ethylamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure compliance with research and development grade standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.