Description

2-(2-(3-Nitrophenyl)-4-Thioxo-5,6,7,8-Tetrahydroquinazolin-1(4H)-Yl)Acetic Acid is a high-value, synthetically derived organic compound with a complex heterocyclic structure, serving as a critical advanced intermediate in modern chemical synthesis. Its molecular architecture, featuring a tetrahydroquinazolinone core and a nitrophenyl substituent, makes it a versatile building block for developing novel active compounds. This product is primarily targeted at research and development laboratories, pharmaceutical companies, and fine chemical manufacturers engaged in creating new materials, agrochemicals, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzymatic pathways where the quinazolinone scaffold is pharmacologically active.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a building block for synthesizing specialized organic ligands, dyes, or photoactive compounds for advanced material applications.
• Chemical Biology & Proteomics: Employed as a molecular probe or a scaffold for designing enzyme inhibitors and other bioactive tools in biochemical research.
• Academic & Contract Research: Essential for synthetic organic chemistry research in universities and CROs (Contract Research Organizations) exploring new heterocyclic reactions and methodologies.
• Fine Chemical Synthesis: A versatile intermediate for the custom synthesis of complex, high-value molecules for various industrial and research purposes.

Basic Information

Product Name	2-(2-(3-Nitrophenyl)-4-Thioxo-5,6,7,8-Tetrahydroquinazolin-1(4H)-Yl)Acetic Acid
CAS No.	462069-18-7
Molecular Formula	C₁₆H₁₅N₃O₄S
Molecular Weight	345.37 g/mol
Synonyms	2-[2-(3-Nitrophenyl)-4-sulfanylidene-5,6,7,8-tetrahydro-1H-quinazolin-1-yl]acetic acid; 2-(2-(3-Nitrophenyl)-4-thioxo-1,4,5,6,7,8-hexahydroquinazolin-1-yl)acetic acid; 1H-Quinazolin-1-acetic acid, 5,6,7,8-tetrahydro-2-(3-nitrophenyl)-4-thioxo-; Acetic acid, 2-[2-(3-nitrophenyl)-4-thioxo-5,6,7,8-tetrahydro-1(4H)-quinazolinyl]-; 462069-18-7; 2-(2-(3-Nitrophenyl)-4-thioxo-5,6,7,8-tetrahydroquinazolin-1-yl)acetic acid
EINECS	Contact for details

Quality Control

Every batch of 2-(2-(3-Nitrophenyl)-4-Thioxo-5,6,7,8-Tetrahydroquinazolin-1(4H)-Yl)Acetic Acid is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.