Description

4H-Pyrrolo[3,4-C]Quinolin-4-One, 2,5-Dihydro-5-Hydroxy-3-Methyl- (9Ci) is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily utilized by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders or possessing kinase inhibitory activity.
• Organic Synthesis Building Block: Used in research-scale and pilot-scale organic synthesis to construct fused pyrroloquinoline ring systems, which are privileged structures in medicinal chemistry.
• Chemical Reference Standard: Employed as a high-purity analytical standard for method development, quality control, and regulatory submissions in pharmaceutical analysis.
• Academic & Industrial R&D: Facilitates exploratory chemistry in academic settings and industrial R&D departments for developing new chemical entities (NCEs) and exploring structure-activity relationships (SAR).
• Process Chemistry Development: Used in route scouting and optimization studies for the scalable production of target molecules in the pharmaceutical pipeline.

Basic Information

Product Name	4H-Pyrrolo[3,4-C]Quinolin-4-One, 2,5-Dihydro-5-Hydroxy-3-Methyl- (9Ci)
CAS No.	460077-24-1
Molecular Formula	C12H10N2O2
Molecular Weight	214.22 g/mol
Synonyms	2,5-Dihydro-5-hydroxy-3-methyl-4H-pyrrolo[3,4-c]quinolin-4-one; 5-Hydroxy-3-methyl-2,5-dihydro-4H-pyrrolo[3,4-c]quinolin-4-one; 3-Methyl-5-hydroxy-2,5-dihydro-4H-pyrrolo[3,4-c]quinolin-4-one; Pyrrolo[3,4-c]quinolin-4-one, 2,5-dihydro-5-hydroxy-3-methyl-; CAS 460077-24-1
EINECS	Contact for details

Quality Control

Our 4H-Pyrrolo[3,4-C]Quinolin-4-One, 2,5-Dihydro-5-Hydroxy-3-Methyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) detailing all test results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.