Description

Ethyl 6,8-Dichloro-4-[(3-Hydroxypropyl)Amino]-3-Quinolinecarboxylate is a high-purity, synthetically valuable quinoline derivative. This compound serves as a critical advanced pharmaceutical intermediate in the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex heterocyclic molecules for therapeutic applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly in oncology and anti-infective research.
• Chemical Synthesis Reagent: Used in organic synthesis for constructing complex quinoline-based molecular scaffolds.
• Research & Development: Essential material for medicinal chemistry programs exploring structure-activity relationships (SAR) of quinoline derivatives.
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in API manufacturing.
• Precursor for Functionalized Quinolines: The reactive functional groups allow for further derivatization to create libraries of specialized compounds.

Basic Information

Product Name	Ethyl 6,8-Dichloro-4-[(3-Hydroxypropyl)Amino]-3-Quinolinecarboxylate
CAS No.	459418-86-1
Molecular Formula	C15H16Cl2N2O3
Molecular Weight	343.21 g/mol
Synonyms	Ethyl 4-[(3-Hydroxypropyl)amino]-6,8-dichloroquinoline-3-carboxylate; 6,8-Dichloro-4-[(3-hydroxypropyl)amino]-3-quinolinecarboxylic acid ethyl ester; 4-[(3-Hydroxypropyl)amino]-6,8-dichloroquinoline-3-carboxylic Acid Ethyl Ester; 3-Quinolinecarboxylic acid, 6,8-dichloro-4-[(3-hydroxypropyl)amino]-, ethyl ester; CAS 459418-86-1
EINECS	Contact for details

Quality Control

Our Ethyl 6,8-Dichloro-4-[(3-Hydroxypropyl)Amino]-3-Quinolinecarboxylate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.