Description

6-Bromo-n-(4-Fluorophenyl)-4-Quinazolinamine is a high-purity, advanced pharmaceutical intermediate with significant synthetic utility. This compound is valued for its role as a key building block in the research and development of novel small-molecule therapeutics, particularly kinase inhibitors. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in drug discovery programs targeting oncology and inflammatory diseases.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of targeted kinase inhibitors for oncology research.
• Drug Discovery Scaffold: Serves as a core structural motif for medicinal chemistry optimization and structure-activity relationship (SAR) studies.
• Biochemical Research: Used as a reference standard or probe compound in enzymatic assays and biological screening.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct complex heterocyclic molecules for various applications.
• Academic Research: Utilized in university and institutional labs for developing new synthetic methodologies and exploring chemical biology.

Basic Information

Product Name	6-Bromo-n-(4-Fluorophenyl)-4-Quinazolinamine
CAS No.	459418-63-4
Molecular Formula	C14H9BrFN3
Molecular Weight	318.15 g/mol
Synonyms	6-Bromo-N-(4-fluorophenyl)quinazolin-4-amine; 4-Quinazolinamine, 6-bromo-N-(4-fluorophenyl)-; 6-Bromo-4-((4-fluorophenyl)amino)quinazoline; N-(4-Fluorophenyl)-6-bromoquinazolin-4-amine; 459418-63-4; 6-Bromo-N-(4-fluorophenyl)-4-quinazolinamine
EINECS	Contact for details

Quality Control

Our 6-Bromo-n-(4-Fluorophenyl)-4-Quinazolinamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with client specifications and industry standards for research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.