Description

6,6,8-Trimethyl-5,6-Dihydro-1H-Pyrrolo[2,3-G]Quinoline is a high-purity, advanced pharmaceutical intermediate with a complex fused heterocyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and other specialized drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates, especially those targeting specific biological pathways.
• Organic Synthesis Building Block: Used in research and development for constructing novel heterocyclic compounds with potential biological activity.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies in academic and industrial drug discovery projects.
• Chemical Reference Standard: Employed as a high-purity analytical standard for method development and quality control in API manufacturing.

Basic Information

Product Name	6,6,8-Trimethyl-5,6-Dihydro-1H-Pyrrolo[2,3-G]Quinoline
CAS No.	459169-60-9
Molecular Formula	C₁₄H₁₆N₂
Molecular Weight	212.29 g/mol
Synonyms	5,6-Dihydro-6,6,8-trimethyl-1H-pyrrolo[2,3-g]quinoline; 6,6,8-Trimethyl-5,6-dihydro-1H-pyrrolo[2,3-g]quinoline; Pyrroloquinoline derivative; Fused tricyclic heterocycle; Advanced pharmaceutical intermediate
EINECS	Contact for details

Quality Control

Our production of 6,6,8-Trimethyl-5,6-Dihydro-1H-Pyrrolo[2,3-G]Quinoline adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.