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2-({2-[2-(2-Isopropyl-5-Methylphenoxy)Acetyl]Hydrazino}Carbonyl)Benzoic Acid CAS NO 458526-46-0
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CAS No.:458526-46-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-({2-[2-(2-Isopropyl-5-Methylphenoxy)Acetyl]Hydrazino}Carbonyl)Benzoic Acid is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is valued for its role as a key building block in medicinal chemistry, enabling the development of targeted therapeutic agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel small-molecule drugs, particularly in areas requiring sophisticated molecular architectures.
Application
- Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of proprietary drug candidates and active pharmaceutical ingredients (APIs).
- Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic molecules.
- Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and process development projects.
- Academic Research: Employed in university and institutional labs for investigating new organic reactions and synthetic methodologies.
- Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
Basic Information
| Product Name | 2-({2-[2-(2-Isopropyl-5-Methylphenoxy)Acetyl]Hydrazino}Carbonyl)Benzoic Acid |
| CAS No. | 458526-46-0 |
| Molecular Formula | C21H22N2O5 |
| Molecular Weight | 382.41 g/mol |
| Synonyms | 2-[[2-[2-(5-Methyl-2-propan-2-ylphenoxy)acetyl]hydrazinyl]carbonyl]benzoic acid; 2-({2-[2-(2-Isopropyl-5-methylphenoxy)acetyl]hydrazino}carbonyl)benzoic acid; Benzoic acid, 2-[[2-[2-(5-methyl-2-(1-methylethyl)phenoxy)acetyl]hydrazino]carbonyl]-; 2-(2-(2-(2-Isopropyl-5-methylphenoxy)acetyl)hydrazinecarbonyl)benzoic acid |
| EINECS | Contact for details |
Quality Control
Our production of 2-({2-[2-(2-Isopropyl-5-Methylphenoxy)Acetyl]Hydrazino}Carbonyl)Benzoic Acid adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed in a dry environment.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Assay (HPLC) | ≥ 98.0% |
| Related Substances (HPLC) | Total impurities ≤ 2.0% Any single impurity ≤ 0.5% |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Why choose US
Trusted Manufacturer
With our own production facilities, we ensure consistent quality, reliable supply, and full traceability.
Rigorous Quality Assurance
Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
Advanced R&D Expertise
Our in-house lab drives process innovation, new product development, and tailored synthesis solutions.






