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Ethanol, 2-[[2-(Aminooxy)Ethyl]Methylamino]- (9Ci) CAS NO 454701-73-6


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CAS No.:454701-73-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Ethanol, 2-[[2-(Aminooxy)Ethyl]Methylamino]- (9Ci) is a specialized bifunctional organic compound featuring both an aminooxy and a tertiary amine group. This unique structure makes it a valuable versatile linker and building block in advanced chemical synthesis, particularly for the formation of stable oxime bonds. It is primarily needed by pharmaceutical researchers, bioconjugation specialists, and material scientists developing targeted drug delivery systems, diagnostic reagents, and functionalized polymers.

Application

  • Bioconjugation and Antibody-Drug Conjugate (ADC) Development: Serves as a key heterobifunctional crosslinker for attaching cytotoxic drugs, fluorescent dyes, or other payloads to antibodies, proteins, or peptides via oxime chemistry.
  • Pharmaceutical Intermediate: Used in the synthesis of more complex active pharmaceutical ingredients (APIs) and prodrugs that require a cleavable or stable linker moiety.
  • Polymer Functionalization: Acts as a monomer or modifier to introduce reactive aminooxy groups into polymer backbones for creating smart materials, hydrogels, or surface coatings.
  • Diagnostic Reagent Synthesis: Employed in the production of contrast agents, imaging probes, and assay components where specific, stable labeling is critical.
  • Chemical Biology Research: A valuable tool for site-specific protein modification, surface immobilization of biomolecules, and exploring new bioorthogonal reaction pathways.
  • Material Science: Used in the development of functionalized nanoparticles, dendrimers, and other nanomaterials for targeted delivery and sensing applications.

Basic Information

Product Name Ethanol, 2-[[2-(Aminooxy)Ethyl]Methylamino]- (9Ci)
CAS No. 454701-73-6
Molecular Formula C5H14N2O2
Molecular Weight 134.18 g/mol
Synonyms 2-[[2-(Aminooxy)ethyl]methylamino]ethanol; N-Methyl-N-(2-aminooxyethyl)ethanolamine; 2-[Methyl[2-(aminooxy)ethyl]amino]ethanol; Amino-PEG3-alcohol derivative; Heterobifunctional aminooxy-amine linker; O-(2-Aminoethyl)-N-methylhydroxylamine ethanol adduct
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Quality Control

Our production of Ethanol, 2-[[2-(Aminooxy)Ethyl]Methylamino]- adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for critical research and development applications. Certificates of Analysis (COA) are provided with each shipment, detailing key parameters such as purity, identity, and impurity profiles. We support compliance with relevant frameworks for research chemicals and can discuss custom purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 95.0%
Water Content (KF) ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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