Description

n-Boc-3-Thiomorpholinopropylamine is a high-purity, protected amine building block essential for advanced organic synthesis. This compound matters as a versatile intermediate, enabling the controlled introduction of the thiomorpholine moiety into complex molecular architectures. It is primarily needed by pharmaceutical and agrochemical R&D teams for the development of new active ingredients, particularly in medicinal chemistry for creating novel drug candidates.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of potential drug candidates, especially those targeting neurological or oncological pathways.
• Peptide Mimetics & Conjugation: Used to incorporate the thiomorpholine scaffold into peptide backbones or for linker chemistry in antibody-drug conjugates (ADCs).
• Agrochemical Research: Serves as a building block for developing new crop protection agents and herbicides.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and protein interactions.
• Material Science: Potential monomer or modifier in the synthesis of specialized polymers with unique properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific, multi-step synthetic projects.

Basic Information

Item	Detail
Product Name	n-Boc-3-Thiomorpholinopropylamine
CAS No.	454701-66-7
Molecular Formula	C12H24N2O2S
Molecular Weight	260.40 g/mol
Synonyms	tert-Butyl (3-(thiomorpholino)propyl)carbamate; 1-Boc-3-thiomorpholinopropylamine; 3-(Thiomorpholino)propylcarbamic Acid tert-Butyl Ester; N-Boc-3-Thiomorpholinopropylamine; N-(tert-Butoxycarbonyl)-3-thiomorpholinopropylamine; 3-Thiomorpholinopropylamine, N-Boc-; tert-Butyl N-[3-(thiomorpholin-4-yl)propyl]carbamate
EINECS	Contact for details

Quality Control

Our n-Boc-3-Thiomorpholinopropylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure compliance with high-grade chemical standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.