Description

2-Methoxy-4-Nitro-1-(Trifluoromethyl)Benzene is a high-value, multi-functional aromatic intermediate characterized by its nitro and trifluoromethyl substituents. This compound is essential for synthesizing advanced materials and active pharmaceutical ingredients (APIs) where electronic and steric properties are critical. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those requiring the bioisosteric and lipophilicity-enhancing trifluoromethyl group.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the nitro group serves as a versatile handle for further chemical transformations.
• Liquid Crystal & OLED Material Research: Serves as a precursor in the development of organic electronic materials due to its electron-withdrawing substituents that can tune optical and electronic properties.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized nitro- and methoxy-substituted dyes and pigments for high-performance applications.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for creating complex biaryl structures.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D exploring new synthetic methodologies and novel chemical entities.

Basic Information

Item	Detail
Product Name	2-Methoxy-4-Nitro-1-(Trifluoromethyl)Benzene
CAS No.	453560-74-2
Molecular Formula	C9H6F3NO3
Molecular Weight	233.14 g/mol
Synonyms	1-Methoxy-2-nitro-4-(trifluoromethyl)benzene; 2-Nitro-4-(trifluoromethyl)anisole; 4-(Trifluoromethyl)-2-nitroanisole; 2-Methoxy-4-nitrobenzotrifluoride; 4-Nitro-2-methoxybenzotrifluoride; 2-Nitro-α,α,α-trifluoro-p-anisole; 4-(Trifluoromethyl)-2-nitro-1-methoxybenzene
EINECS	Contact for details

Quality Control

Our 2-Methoxy-4-Nitro-1-(Trifluoromethyl)Benzene is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.