Description

6-Azatricyclo[3.2.1.02,4]Octan-7-One,(1R,2S,4R,5S)-(9Ci) is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound is valued for its rigid, complex tricyclic scaffold which serves as a critical building block in modern medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates and novel molecular entities.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its constrained three-dimensional geometry.
• Asymmetric Synthesis: Serves as a precursor or template in catalytic asymmetric reactions to introduce specific stereocenters.
• CNS Drug Development: Exploration of applications in neurological disorders, leveraging its bridged bicyclic amine structure.
• Protease Inhibitor Scaffold: Potential use in the design of inhibitors for various viral or metabolic proteases.
• Chemical Biology: Incorporation into molecular probes for studying enzyme mechanisms or protein-ligand interactions.

Basic Information

Product Name	6-Azatricyclo[3.2.1.02,4]Octan-7-One,(1R,2S,4R,5S)-(9Ci)
CAS No.	452324-62-8
Molecular Formula	C7H9NO
Molecular Weight	123.15 g/mol
Synonyms	(1R,2S,4R,5S)-6-Azatricyclo[3.2.1.02,4]octan-7-one; (1R,2S,4R,5S)-6-Aza-tricyclo[3.2.1.02,4]octan-7-one; 6-Azatricyclo[3.2.1.02,4]octan-7-one, (1R,2S,4R,5S)-; 452324-62-8; (1R,2S,4R,5S)-6-Azatricyclo[3.2.1.02,4]octan-7-one (9CI); 7-Oxo-6-azatricyclo[3.2.1.02,4]octane, (1R,2S,4R,5S)-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with a typical purity of ≥97% (by HPLC), meeting the stringent requirements for pharmaceutical R&D. Identity is confirmed via spectroscopic methods (NMR, IR, MS). Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.