Description

4-((Tosylamino)Methyl)Benzoic Acid CAS NO 451484-11-0 is a high-purity, functionalized benzoic acid derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular structure, which incorporates both a tosyl-protected amine and a carboxylic acid group, enabling precise chemical modifications. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Research: Used in developing new active ingredients for crop protection products, such as herbicides and fungicides.
• Peptide Mimetics & Conjugation: The carboxylic acid moiety facilitates coupling reactions for creating peptide-like structures or bioconjugates.
• Material Science: Serves as a monomer or functionalizing agent in the production of specialty polymers and advanced organic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and mechanisms.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring specific, high-value aromatic intermediates.

Basic Information

Product Name	4-((Tosylamino)Methyl)Benzoic Acid
CAS No.	451484-11-0
Molecular Formula	C15H15NO4S
Molecular Weight	305.35 g/mol
Synonyms	4-[(4-Methylphenyl)sulfonylamino]methyl]benzoic Acid; p-((p-Toluenesulfonamido)methyl)benzoic Acid; Benzoic acid, 4-[[[(4-methylphenyl)sulfonyl]amino]methyl]-; N-[(4-Carboxyphenyl)methyl]-4-methylbenzenesulfonamide; Tosyl-AMBA; 4-(Tosylaminomethyl)benzoic Acid
EINECS	Contact for details

Quality Control

Every batch of 4-((Tosylamino)Methyl)Benzoic Acid is manufactured under strict quality management protocols. We employ advanced analytical techniques, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the exacting standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.