Description

8-Quinolinol, 5,6,7,8-Tetrahydro-, (8R)- (9Ci) is a chiral, hydrogenated derivative of 8-hydroxyquinoline, a compound class renowned for its versatile chelating properties. This specific stereoisomer is of significant interest in advanced pharmaceutical research and fine chemical synthesis, where precise molecular configuration is critical for biological activity and process selectivity. It serves as a valuable chiral building block or ligand for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective agents.
• Catalyst Ligand: Utilized as a chiral ligand in asymmetric catalysis to induce stereoselectivity in synthetic transformations, such as hydrogenations or cross-coupling reactions.
• Agrochemical Research: Employed in the synthesis of advanced, stereochemically-defined crop protection agents and pesticides.
• Metal Chelation Studies: Used in academic and industrial research to study metal ion coordination chemistry due to its modified quinoline structure.
• Fine Chemical Synthesis: Serves as a specialized building block for creating complex molecules in custom synthesis and contract manufacturing projects.

Basic Information

Product Name	8-Quinolinol, 5,6,7,8-Tetrahydro-, (8R)- (9Ci)
CAS No.	451466-81-2
Molecular Formula	C9H11NO
Molecular Weight	149.19 g/mol
Synonyms	(8R)-5,6,7,8-Tetrahydro-8-quinolinol; (R)-5,6,7,8-Tetrahydroquinolin-8-ol; (8R)-5,6,7,8-Tetrahydro-8-hydroxyquinoline; (R)-8-Hydroxy-1,2,3,4-tetrahydroquinoline; 8-Hydroxy-1,2,3,4-tetrahydroquinoline (R)-; Tetrahydro-8-quinolinol, (8R)-; Chiral Tetrahydro-8-hydroxyquinoline
EINECS	Contact for details

Quality Control

Our 8-Quinolinol, 5,6,7,8-Tetrahydro-, (8R)- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assay and impurity profiling, to ensure it meets the exacting standards required for research and synthesis. A Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral excess, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.