Description

8-Quinolinol, 5,6,7,8-Tetrahydro-, (8S)- (9Ci) is a chiral, saturated derivative of the versatile 8-hydroxyquinoline scaffold, distinguished by its specific (8S) stereochemistry. This compound matters as a high-value building block and ligand precursor for advanced chemical synthesis, offering unique steric and electronic properties compared to its planar aromatic counterpart. It is primarily needed by researchers and manufacturers in the pharmaceutical and fine chemical industries for developing novel active ingredients and catalytic systems.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic agents, particularly where the tetrahydroquinoline core is pharmacologically relevant.
• Asymmetric Catalysis: Used as a precursor for synthesizing chiral ligands in metal-catalyzed reactions, enabling the production of enantiomerically pure compounds.
• Organic Synthesis Building Block: Employed in the construction of complex nitrogen-containing heterocycles for material science and agrochemical research.
• Chelating Agent Research: Investigated for its metal-chelating properties in analytical chemistry and as a model for designing new sequestering agents.
• Academic & R&D: Utilized in university and corporate research laboratories for methodological studies and exploring new chemical spaces.

Basic Information

Product Name	8-Quinolinol, 5,6,7,8-Tetrahydro-, (8S)- (9Ci)
CAS No.	451466-79-8
Molecular Formula	C9H11NO
Molecular Weight	149.19 g/mol
Synonyms	(8S)-5,6,7,8-Tetrahydro-8-quinolinol; (8S)-5,6,7,8-Tetrahydroquinolin-8-ol; (S)-5,6,7,8-Tetrahydro-8-hydroxyquinoline; (S)-8-Hydroxy-1,2,3,4-tetrahydroquinoline; Light-sensitive (8S)-Tetrahydro-8-quinolinol; Chiral Tetrahydro-8-hydroxyquinoline; Ligand precursor 451466-79-8
EINECS	Contact for details

Quality Control

Our production of 8-Quinolinol, 5,6,7,8-Tetrahydro-, (8S)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized by modern analytical techniques, including HPLC, GC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.