Description

(R)-3-Phenyl-Piperidine Hydrochloride is a high-purity chiral building block and intermediate of significant importance in modern synthetic chemistry. Its value lies in its well-defined stereochemistry, which is critical for the development of enantiomerically pure pharmaceuticals and advanced materials. This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for applications in drug discovery, process development, and the synthesis of complex organic molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of central nervous system (CNS) active drugs, receptor modulators, and other bioactive molecules.
• Asymmetric Synthesis: Used as a stereochemically defined scaffold or ligand precursor in catalytic asymmetric reactions.
• Agrochemical Research: Intermediate in the synthesis of novel, enantiomerically pure pesticides and herbicides.
• Chemical Biology: Building block for creating molecular probes and tools to study biological pathways and protein interactions.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and optimization of API (Active Pharmaceutical Ingredient) manufacturing processes.
• Academic Research: Valuable compound for methodological studies in organic synthesis and medicinal chemistry within university and institutional labs.

Basic Information

Product Name	(R)-3-Phenyl-Piperidine Hydrochloride
CAS No.	450416-58-7
Molecular Formula	C11H16ClN
Molecular Weight	197.70 g/mol
Synonyms	(R)-3-Phenylpiperidine hydrochloride; (R)-3-Phenylpiperidine HCl; (3R)-3-Phenylpiperidine hydrochloride; (R)-3-Phenylpiperidinium chloride; (R)-3-Phenyl-piperidine hydrochloride; Piperidine, 3-phenyl-, hydrochloride, (3R)-; (R)-3-Phenylpiperidine monohydrochloride; (R)-NSC 339539 hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-3-Phenyl-Piperidine Hydrochloride is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification, to meet the stringent requirements of advanced R&D and scale-up activities. A Certificate of Analysis (COA) detailing identity, purity (HPLC/Chiral HPLC), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.