Description

3Ah-Indene-3A-Carbonitrile,Octahydro-7-Hydroxy-7-Methyl-1-Methylene-,(3Ar,7S,7Ar)-Rel-(9Ci) is a high-purity, advanced pharmaceutical intermediate with a complex, stereochemically defined polycyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular architecture. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and complex organic syntheses. The product is supplied with a Certificate of Analysis to ensure batch-to-batch consistency and meets the stringent purity requirements for pharmaceutical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-inflammatory research.
• Organic Synthesis Research: Used in academic and industrial laboratories for methodological studies involving complex cyclization, hydroxylation, and nitrile chemistry.
• Asymmetric Catalysis Studies: Acts as a substrate or ligand precursor in the development of new asymmetric synthetic methodologies due to its defined stereocenters.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals and other high-value, complex organic molecules.
• Reference Standard: Can be used as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	3Ah-Indene-3A-Carbonitrile,Octahydro-7-Hydroxy-7-Methyl-1-Methylene-,(3Ar,7S,7Ar)-Rel-(9Ci)
CAS No.	450406-25-4
Molecular Formula	C12H17NO
Molecular Weight	191.27 g/mol
Synonyms	(3aR,7S,7aR)-rel-Octahydro-7-hydroxy-7-methyl-1-methylene-3aH-indene-3a-carbonitrile; rel-(3aR,7S,7aR)-Octahydro-7-hydroxy-7-methyl-1-methylene-3aH-indene-3a-carbonitrile; 3aH-Indene-3a-carbonitrile, octahydro-7-hydroxy-7-methyl-1-methylene-, (3aR,7S,7aR)-rel-; 450406-25-4; Advanced Indene Carbonitrile Derivative; Chiral Polycyclic Nitrile Intermediate
EINECS	Contact for details

Quality Control

Our 3Ah-Indene-3A-Carbonitrile,Octahydro-7-Hydroxy-7-Methyl-1-Methylene-,(3Ar,7S,7Ar)-Rel-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.