Description

6-(2,4-Difluorophenoxy)-8-Methyl-2-(Methylsulfonyl)Pyrido[2,3-D]Pyrimidin-7(8H)-One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. It serves as a key building block for research and development chemists and production teams in the pharmaceutical and biotechnology sectors.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel drug candidates, especially kinase inhibitors.
• Biochemical Research: Used as a reference standard or a probe molecule in enzymatic and receptor binding studies.
• Agrochemical Development: Serves as a sophisticated scaffold for creating new active ingredients in crop protection research.
• Organic Synthesis: Employed in academic and industrial R&D for constructing complex pyrido[2,3-d]pyrimidine derivatives.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for GMP-scale API production.

Basic Information

Product Name	6-(2,4-Difluorophenoxy)-8-Methyl-2-(Methylsulfonyl)Pyrido[2,3-D]Pyrimidin-7(8H)-One
CAS No.	449808-50-8
Molecular Formula	C₁₆H₁₁F₂N₃O₄S
Molecular Weight	379.34 g/mol
Synonyms	8-Methyl-6-(2,4-difluorophenoxy)-2-(methylsulfonyl)pyrido[2,3-d]pyrimidin-7(8H)-one; 6-(2,4-Difluorophenoxy)-8-methyl-2-methylsulfonyl-pyrido[2,3-d]pyrimidin-7-one; 449808-50-8; Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-(2,4-difluorophenoxy)-8-methyl-2-(methylsulfonyl)-; 2-(Methylsulfonyl)-6-(2,4-difluorophenoxy)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one
EINECS	Contact for details

Quality Control

Our 6-(2,4-Difluorophenoxy)-8-Methyl-2-(Methylsulfonyl)Pyrido[2,3-D]Pyrimidin-7(8H)-One is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.