Description

3-(2-[3-(Trifluoromethyl)Phenoxy]Phenyl)Acrylic Acid is a specialized fluorinated acrylic acid derivative, serving as a high-value synthetic intermediate in advanced organic synthesis. Its core value lies in the unique combination of the acrylic acid moiety and the trifluoromethylphenoxy group, which imparts desirable properties like enhanced lipophilicity and metabolic stability to target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially those targeting inflammation, CNS disorders, or metabolic diseases.
• Agrochemical Research: Used in creating novel herbicides, fungicides, or insecticides where the trifluoromethyl group can improve biological activity and environmental persistence.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored surface properties or refractive indices.
• Liquid Crystal & OLED Materials: A potential intermediate for synthesizing fluorinated components used in display and lighting technologies.
• Chemical Biology Probes: Utilized in the design of activity-based probes or labeled compounds for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific research projects and scale-up campaigns.

Basic Information

Product Name	3-(2-[3-(Trifluoromethyl)Phenoxy]Phenyl)Acrylic Acid
CAS No.	449778-81-8
Molecular Formula	C16H11F3O3
Molecular Weight	308.25 g/mol
Synonyms	2-[3-(Trifluoromethyl)phenoxy]cinnamic acid; (E)-3-[2-[3-(Trifluoromethyl)phenoxy]phenyl]prop-2-enoic acid; 3-[2-(3-Trifluoromethylphenoxy)phenyl]acrylic acid; α-(2-((3-(Trifluoromethyl)phenyl)oxy)phenyl)acrylic acid; (E)-3-(2-(3-(Trifluoromethyl)phenoxy)phenyl)acrylic acid; 3-(2-(3-(Trifluoromethyl)phenoxy)phenyl)-2-propenoic acid; 449778-81-8; 3-(2-(3-(Trifluoromethyl)phenoxy)phenyl)acrylic acid
EINECS	Contact for details

Quality Control

Our 3-(2-[3-(Trifluoromethyl)Phenoxy]Phenyl)Acrylic Acid is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. We employ advanced analytical techniques, including HPLC, NMR, and MS, for comprehensive characterization and purity verification. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of heat. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.