Description

3-Butyn-2-Ol, 4-(1-Cyclohexen-1-Yl)-, (2R)- (9Ci) is a chiral, optically active building block featuring both an alkyne and an alkene functional group on a cyclohexene scaffold. This unique molecular architecture makes it a highly valuable intermediate for the synthesis of complex, stereodefined molecules in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients, catalysts, and functional materials. The compound's defined stereochemistry at the 2-position is critical for achieving specific biological activity or material properties in the final product.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and oncology.
• Agrochemical Research: Used in the development of novel pesticides and herbicides where the stereochemistry and functional groups are essential for bioactivity and selectivity.
• Catalyst & Ligand Synthesis: Serves as a precursor for creating sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Employed in the research of advanced polymers and functional organic materials that require precise molecular geometry.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting fundamental research in organic synthesis and methodology development.

Basic Information

Item	Details
Product Name	3-Butyn-2-Ol, 4-(1-Cyclohexen-1-Yl)-, (2R)- (9Ci)
CAS No.	449204-44-8
Molecular Formula	C10H14O
Molecular Weight	150.22 g/mol
Synonyms	(2R)-4-(Cyclohex-1-en-1-yl)but-3-yn-2-ol; (R)-4-(1-Cyclohexen-1-yl)-3-butyn-2-ol; (R)-4-Cyclohex-1-en-1-ylbut-3-yn-2-ol; (2R)-4-(1-Cyclohexenyl)-3-butyn-2-ol; (R)-4-(Cyclohex-1-enyl)but-3-yn-2-ol; (R)-4-(Cyclohexen-1-yl)-3-butyn-2-ol; (R)-4-(1-Cyclohexenyl)but-3-yn-2-ol; (R)-4-(Cyclohex-1-en-1-yl)but-3-yn-2-ol
EINECS	Contact for details

Quality Control

Our 3-Butyn-2-Ol, 4-(1-Cyclohexen-1-Yl)-, (2R)- (9Ci) is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. All batches are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and key analytical data. We support our clients with full traceability and documentation to meet the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.