Description

1,2,3,4-Tetrahydro-[2,7]Naphthyridine Dihydrochloride is a high-purity, heterocyclic organic compound that serves as a critical building block in advanced pharmaceutical research and development. Its value lies in its role as a versatile synthetic intermediate for creating novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting the central nervous system and metabolic disorders. This compound is essential for medicinal chemists and R&D teams in the pharmaceutical, biotechnology, and fine chemical industries who require reliable, high-quality intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Development: Serves as a building block in the multi-step synthesis of complex target molecules for clinical trials.
• Biochemical Tool Compound: Employed in biochemical assays and as a reference standard for pharmacological studies.
• Fine Chemical Synthesis: Utilized in the production of specialty chemicals and advanced materials requiring specific heterocyclic architectures.

Basic Information

Item	Detail
Product Name	1,2,3,4-Tetrahydro-[2,7]Naphthyridine Dihydrochloride
CAS No.	449175-32-0
Molecular Formula	C8H12N2·2HCl
Molecular Weight	221.11 g/mol
Synonyms	1,2,3,4-Tetrahydro-2,7-naphthyridine dihydrochloride; 2,7-Naphthyridine, 1,2,3,4-tetrahydro-, dihydrochloride; THN Dihydrochloride; [2,7]Naphthyridine, 1,2,3,4-tetrahydro-, hydrochloride (1:2); 1,2,3,4-Tetrahydro-2,7-naphthyridine HCl; 449175-32-0 (CAS); Tetrahydro[2,7]naphthyridine dihydrochloride
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydro-[2,7]Naphthyridine Dihydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.