Description

6-Aminooxy-Hexanoic Acid is a bifunctional organic compound featuring both an aminooxy and a carboxylic acid group, making it a versatile linker and building block in chemical synthesis. This unique structure is critical for creating stable conjugates and functionalized materials through oxime ligation and other coupling reactions. It is primarily sought after by researchers and manufacturers in the pharmaceutical, bioconjugation, and advanced materials sectors for developing targeted drug delivery systems, diagnostic probes, and specialty polymers.

Application

• Bioconjugation and Protein Labeling: Used as a heterobifunctional crosslinker to attach drugs, fluorophores, or other molecules to proteins, antibodies, or peptides via its aminooxy group.
• Drug Discovery & Development: Serves as a key intermediate in the synthesis of antibody-drug conjugates (ADCs) and other targeted therapeutics.
• Polymer Functionalization: Enables the introduction of reactive aminooxy groups into polymer backbones for creating smart, responsive materials.
• Surface Modification: Used to functionalize nanoparticles, biosensors, and solid supports for immobilizing biomolecules.
• Chemical Biology Probes: Acts as a tool compound for studying biological processes through site-specific labeling of carbonyl-containing biomolecules.
• Peptide Synthesis: Incorporated into peptides as a modified amino acid to introduce specific chemical handles for further modification.

Basic Information

Item	Details
Product Name	6-Aminooxy-Hexanoic Acid
CAS No.	448954-98-1
Molecular Formula	C6H13NO3
Molecular Weight	147.17 g/mol
Synonyms	6-(Aminooxy)hexanoic Acid; 6-Aminooxycaproic Acid; Aminooxy-PEG5-acid; O-(5-Carboxypentyl)hydroxylamine; 5-(Aminooxymethyl)pentanoic Acid; Hexanoic acid, 6-aminooxy-; Aminooxyhexanoic Acid
EINECS	Contact for details

Quality Control

Our 6-Aminooxy-Hexanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity. Allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.