Description

1-Bromo-4-[(4-Chlorophenyl)Methoxy]Benzene is a high-purity, diaryl ether-based organic intermediate of significant importance in advanced chemical synthesis. Its unique structure, featuring both bromo and chloro substituents, makes it a versatile and valuable building block for the development of complex molecules. This compound is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Serves as a critical building block for developing new-generation herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Liquid Crystal & OLED Material Research: Used in the research and development of advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Employed to introduce specific functional groups into polymer chains, enhancing properties like thermal stability, flame retardancy, or chemical resistance.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) due to the reactive bromine atom, enabling the construction of complex biaryl systems.
• Organic Synthesis & Chemical Research: A valuable reagent for academic and industrial R&D chemists exploring new synthetic methodologies and creating novel chemical entities.

Basic Information

Product Name	1-Bromo-4-[(4-Chlorophenyl)Methoxy]Benzene
CAS No.	446849-20-3
Molecular Formula	C13H10BrClO
Molecular Weight	297.57 g/mol
Synonyms	4-Bromophenyl 4-chlorobenzyl ether; 1-Bromo-4-(4-chlorobenzyloxy)benzene; (4-Bromophenoxy)methyl-4-chlorobenzene; 4-Chlorobenzyl 4-bromophenyl ether; p-Bromophenyl p-chlorobenzyl ether; 4'-Chloro-4-bromodiphenyl ether (ambiguous, verify structure); Benzene, 1-bromo-4-[(4-chlorophenyl)methoxy]-
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-[(4-Chlorophenyl)Methoxy]Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storage under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.