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1H-Pyrrolo[2,3-C]Pyridine-7-Carbonitrile,4-Fluoro-(9Ci) CAS NO 446284-50-0


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CAS No.:446284-50-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1H-Pyrrolo[2,3-C]Pyridine-7-Carbonitrile,4-Fluoro-(9Ci) is a high-purity, fluorinated heterocyclic nitrile building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which serves as a critical precursor for constructing complex pharmacophores and functional materials. This compound is primarily needed by research and development teams in the pharmaceutical, agrochemical, and material science industries for the discovery and development of novel active ingredients.

Application

  • Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) targeted therapies.
  • Agrochemical Research: Used in the development of new-generation herbicides and pesticides, leveraging its fluorinated heterocyclic structure for enhanced bioactivity and stability.
  • Material Science Precursor: Serves as a monomer or functional unit in the synthesis of specialty polymers, organic semiconductors, and liquid crystals.
  • Chemical Biology Probe Synthesis: Employed to create labeled compounds and molecular probes for studying biological pathways and target engagement.
  • Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific research and scale-up projects.
  • Academic & Institutional Research: Utilized in university and government laboratories for fundamental studies in heterocyclic and fluorine chemistry.

Basic Information

Product Name 1H-Pyrrolo[2,3-C]Pyridine-7-Carbonitrile,4-Fluoro-(9Ci)
CAS No. 446284-50-0
Molecular Formula C8H4FN3
Molecular Weight 161.14 g/mol
Synonyms 4-Fluoro-1H-pyrrolo[2,3-c]pyridine-7-carbonitrile; 4-Fluoro-7-cyano-1H-pyrrolo[2,3-c]pyridine; 1H-Pyrrolo[2,3-c]pyridine-7-carbonitrile, 4-fluoro-; 446284-50-0; 4-Fluoro-1H-pyrrolo[2,3-c]pyridine-7-carbonitrile (9CI); 4-Fluoro-7-cyano-1H-pyrrolo[2,3-c]pyridine; 4-Fluoro-1H-pyrrolo[2,3-c]pyridine-7-carbonitrile; 4-Fluoro-7-cyano-1H-pyrrolo[2,3-c]pyridine
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Quality Control

Our 1H-Pyrrolo[2,3-C]Pyridine-7-Carbonitrile,4-Fluoro-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from incompatible materials.

Specification

Item Specification
Appearance White to off-white powder or crystalline solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0% (Area %)
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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