Description

1-Bromo-4-Fluoro-5-Methoxy-2-Nitrobenzene is a high-purity halogenated aromatic building block of significant importance in advanced organic synthesis. Its value lies in its multifunctional structure, which allows for selective chemical transformations, making it a critical intermediate for constructing complex molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing complex aromatic and heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its halogen and nitro groups for further functionalization.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials due to its stable aromatic core and substitutable halogens.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments where the nitro and methoxy groups influence color properties and stability.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) where the bromine atom acts as a leaving group.
• Chemical Research & Development: A versatile reagent for exploring novel organic reactions and synthesizing libraries of compounds for biological screening.

Basic Information

Product Name	1-Bromo-4-Fluoro-5-Methoxy-2-Nitrobenzene
CAS No.	445441-57-6
Molecular Formula	C7H5BrFNO3
Molecular Weight	250.02 g/mol
Synonyms	2-Bromo-5-fluoro-4-methoxy-1-nitrobenzene; 4-Bromo-1-fluoro-2-methoxy-5-nitrobenzene; 5-Bromo-2-fluoro-1-methoxy-4-nitrobenzene; Benzene, 1-bromo-4-fluoro-5-methoxy-2-nitro-; 1-Bromo-4-fluoro-5-methoxy-2-nitro-benzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-Fluoro-5-Methoxy-2-Nitrobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.