Description

Methyl 6-Amino-5-Cyano-2-{[(3-Cyano-6,7,8,9-Tetrahydro-5H-Cyclohepta[B]Pyridin-2-Yl)Sulfanyl]Methyl}-4-(2-Fluoro-5-Methoxyphenyl)-4H-Pyran-3-Carboxylate is a sophisticated, high-purity organic intermediate characterized by its complex heterocyclic structure. This compound is of significant value in advanced pharmaceutical research and development, serving as a critical building block for novel active pharmaceutical ingredients (APIs). It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for synthesizing targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex molecular architectures.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes for new chemical entities.
• API Synthesis: Serves as a crucial building block in the multi-step synthesis of target Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Utilized in the development of specialized probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic Research: Employed in university and institutional labs for cutting-edge research in organic synthesis and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	Methyl 6-Amino-5-Cyano-2-{[(3-Cyano-6,7,8,9-Tetrahydro-5H-Cyclohepta[B]Pyridin-2-Yl)Sulfanyl]Methyl}-4-(2-Fluoro-5-Methoxyphenyl)-4H-Pyran-3-Carboxylate
CAS No.	445384-60-1
Molecular Formula	C28H25FN4O4S
Molecular Weight	540.59 g/mol
Synonyms	6-Amino-5-cyano-2-[[(3-cyano-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-2-yl)thio]methyl]-4-(2-fluoro-5-methoxyphenyl)-4H-pyran-3-carboxylic acid methyl ester; Methyl 6-amino-5-cyano-2-(((3-cyano-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-2-yl)thio)methyl)-4-(2-fluoro-5-methoxyphenyl)-4H-pyran-3-carboxylate; CAS 445384-60-1; 4H-Pyran-3-carboxylic acid, 6-amino-5-cyano-2-[[(3-cyano-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-2-yl)thio]methyl]-4-(2-fluoro-5-methoxyphenyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 6-Amino-5-Cyano-2-{[(3-Cyano-6,7,8,9-Tetrahydro-5H-Cyclohepta[B]Pyridin-2-Yl)Sulfanyl]Methyl}-4-(2-Fluoro-5-Methoxyphenyl)-4H-Pyran-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.