Description

Spiro[2.3]Hexane-4-Carboxylic Acid, 4-Amino-, Ethyl Ester (9Ci) is a specialized spirocyclic organic compound featuring both amino and ester functional groups on a strained bicyclic framework. This unique molecular architecture makes it a valuable and versatile building block for advanced chemical synthesis, particularly in the development of novel pharmacophores and materials with tailored properties. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and antiviral targets.
• Agrochemical Synthesis: Used in the design and synthesis of novel herbicides, fungicides, and insecticides, leveraging its spirocyclic core for enhanced biological activity and selectivity.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to create enantiomerically pure compounds.
• Material Science Research: Employed in the synthesis of specialty polymers, dendrimers, and liquid crystals where the rigid spiro structure imparts specific thermal or optical properties.
• Chemical Biology Probe: Utilized as a scaffold for developing molecular probes and inhibitors to study enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses serving the biotechnology and fine chemical industries.

Basic Information

Product Name	Spiro[2.3]Hexane-4-Carboxylic Acid, 4-Amino-, Ethyl Ester (9Ci)
CAS No.	445306-48-9
Molecular Formula	C9H15NO2
Molecular Weight	169.22 g/mol
Synonyms	Ethyl 4-Aminosipro[2.3]hexane-4-carboxylate; 4-Aminosipro[2.3]hexane-4-carboxylic Acid Ethyl Ester; 1-Azaspiro[2.3]hexane-1-carboxylic Acid, 4-Amino-, Ethyl Ester; 4-Amino-spiro[2.3]hexane-4-carboxylic acid ethyl ester; Spiro[2.3]hexane-4-carboxylic acid, 4-amino-, ethyl ester; 445306-48-9; Ethyl 4-aminospiro[2.3]hexane-4-carboxylate
EINECS	Contact for details

Quality Control

Our Spiro[2.3]Hexane-4-Carboxylic Acid, 4-Amino-, Ethyl Ester (9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specification results are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.