Description

6-Bromo-2-(2-Chlorophenyl)Quinoline-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in research and development pipelines. It is primarily sought by pharmaceutical manufacturers and R&D organizations focused on developing new therapeutic agents, including kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, especially in oncology and anti-inflammatory research.
• Chemical Synthesis Building Block: Used in organic synthesis for constructing quinoline-based molecular frameworks with specific bromo and chloro substituents.
• Research & Development: Essential for medicinal chemistry research in academic institutions and corporate R&D labs for structure-activity relationship (SAR) studies.
• API Development: Employed in the development and scale-up processes for new Active Pharmaceutical Ingredients (APIs).
• Material Science Research: Potential use in the development of organic electronic materials or metal-organic frameworks (MOFs) due to its conjugated system.

Basic Information

Item	Details
Product Name	6-Bromo-2-(2-Chlorophenyl)Quinoline-4-Carboxylic Acid
CAS No.	445289-24-7
Molecular Formula	C₁₆H₉BrClNO₂
Molecular Weight	362.61 g/mol
Synonyms	6-Bromo-2-(2-chlorophenyl)-4-quinolinecarboxylic acid; 2-(2-Chlorophenyl)-6-bromoquinoline-4-carboxylic acid; 4-Quinolinecarboxylic acid, 6-bromo-2-(2-chlorophenyl)-; 445289-24-7; 6-Bromo-2-(o-chlorophenyl)quinoline-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-(2-Chlorophenyl)Quinoline-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to ensure full traceability and compliance with your quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.