Description

2'-Amino-3'-Cyano-1-Methyl-1,3,5',6',7',8'-Hexahydro-2,5'-Dioxospiro[2H-Indol-3,4'-(4'H)-Chromene] is a complex spirocyclic organic compound with significant potential as a key synthetic intermediate. This molecule is valued for its unique structural framework, which combines indole and chromene moieties, making it a versatile building block for advanced chemical synthesis. It is primarily sought after by research institutions and pharmaceutical R&D departments for the development of novel heterocyclic compounds and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Organic Synthesis Building Block: Used in academic and industrial research for constructing complex spirocyclic and fused heterocyclic systems due to its reactive amino and cyano functional groups.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and combinatorial chemistry libraries to explore new bioactive chemical space.
• Agrochemical Development: Potential intermediate for creating new classes of herbicides or fungicides with novel modes of action.
• Dye and Pigment Synthesis: The chromene and indole core can be utilized in the development of specialized organic dyes and functional materials.

Basic Information

Product Name	2'-Amino-3'-Cyano-1-Methyl-1,3,5',6',7',8'-Hexahydro-2,5'-Dioxospiro[2H-Indol-3,4'-(4'H)-Chromene]
CAS No.	445222-91-3
Molecular Formula	C19H17N3O3
Molecular Weight	335.36 g/mol
Synonyms	1-Methyl-2'-amino-3'-cyano-1,3,5',6',7',8'-hexahydro-2,5'-dioxospiro[indole-3,4'-chromene]; 2'-Amino-3'-cyano-1-methylspiro[1,3-dihydro-2H-indole-3,4'-(4'H)-chromene]-2,5'(1'H)-dione; Spiro[indole-3,4'-chromene]-2,5'-dione derivative; CAS 445222-91-3; 1-Methyl-2,5'-dioxospiro[indoline-3,4'-chromene]-2'-amine-3'-carbonitrile; 2'-Amino-3'-cyano-1-methyl-1,3-dihydro-2,5'-dioxospiro[2H-indole-3,4'-chromene]; 1-Methyl-2'-amino-3'-cyano-2,5'-dioxospiro[indoline-3,4'-chromene]
EINECS	Contact for details

Quality Control

Our 2'-Amino-3'-Cyano-1-Methyl-1,3,5',6',7',8'-Hexahydro-2,5'-Dioxospiro[2H-Indol-3,4'-(4'H)-Chromene] is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable, and specifications can be aligned with customer requirements for advanced synthetic work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.