Description

3-Acetyl-1H-Indole-5-Carboxylic Acid is a high-purity indole derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its bifunctional molecular architecture, featuring both a carboxylic acid and an acetyl-substituted indole core, enabling precise chemical modifications. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Research: Used in the development of new-generation herbicides and plant growth regulators that leverage the indole scaffold.
• Material Science: Serves as a monomer or functionalizing agent for creating specialized polymers and organic electronic materials.
• Biochemical Probe Development: Utilized in medicinal chemistry to create molecular probes for studying enzyme inhibition and receptor binding.
• Academic & R&D Synthesis: Employed in university and industrial research laboratories for methodological studies and the construction of complex heterocyclic libraries.

Basic Information

Product Name	3-Acetyl-1H-Indole-5-Carboxylic Acid
CAS No.	444991-59-7
Molecular Formula	C11H9NO3
Molecular Weight	203.19 g/mol
Synonyms	5-Carboxy-3-acetylindole; 3-Acetyl-5-indolecarboxylic Acid; 1H-Indole-5-carboxylic acid, 3-acetyl-; 3-Acetylindole-5-carboxylic Acid; 5-Indolecarboxylic acid, 3-acetyl-
EINECS	Contact for details

Quality Control

Our 3-Acetyl-1H-Indole-5-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its chemical nature, the material should be kept away from strong acids and organic solvents. Keep the container tightly sealed when not in use to maintain integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.