Description

6-Fmoc-Hydrazinonicotinic Acid is a specialized, high-purity building block used in the synthesis of complex organic molecules. This compound matters for its role as a key intermediate in the production of pharmaceuticals and advanced research compounds, offering precise control over molecular assembly. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in peptide synthesis, medicinal chemistry, and the development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis, particularly where a protected hydrazine functionality is required.
• Medicinal Chemistry Research: Serves as a versatile reagent for constructing heterocyclic scaffolds and complex molecular architectures in drug discovery.
• Chemical Biology Probes: Employed in the development of labeled compounds and probes for studying biological mechanisms.
• Fine Chemical Production: Acts as a precursor in the multi-step synthesis of specialty chemicals and advanced materials.
• Academic & Industrial R&D: Utilized in research laboratories for methodological development and the exploration of new synthetic pathways.

Basic Information

Product Name	6-Fmoc-Hydrazinonicotinic Acid
CAS No.	444794-69-8
Molecular Formula	C₂₂H₁₉N₃O₄
Molecular Weight	389.41 g/mol
Synonyms	6-[(9H-Fluoren-9-ylmethoxy)carbonyl]hydrazinyl]nicotinic Acid; Fmoc-Hydrazino-nicotinic Acid; 6-(Fmoc-hydrazino)nicotinic Acid; 2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]hydrazinyl}pyridine-5-carboxylic Acid; 5-Carboxy-2-(N-Fmoc-hydrazino)pyridine; Nα-Fmoc-6-hydrazinonicotinic Acid
EINECS	Contact for details

Quality Control

Our 6-Fmoc-Hydrazinonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under conditions that minimize exposure to ambient light and humidity to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.