Description

1-Bromo-2-(Isobutylsulfonyl)Benzene is a specialized organosulfur compound featuring a bromine substituent and an isobutylsulfonyl group on a benzene ring. This unique structure makes it a valuable high-purity building block and key intermediate in advanced organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, especially those requiring sulfone or aryl bromide functional groups.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the sulfonyl moiety can contribute to biological activity.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.
• Cross-Coupling Reactions: The aryl bromide group makes it a suitable substrate for palladium-catalyzed reactions like Suzuki, Heck, or Buchwald-Hartwig amination.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Ligand and Catalyst Development: Employed as a starting material for creating novel ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	1-Bromo-2-(Isobutylsulfonyl)Benzene
CAS No.	444581-50-4
Molecular Formula	C10H13BrO2S
Molecular Weight	277.18 g/mol
Synonyms	2-Bromo-1-(2-methylpropane-1-sulfonyl)benzene; 1-Bromo-2-(2-methylpropylsulfonyl)benzene; o-Bromophenyl isobutyl sulfone; 2-Bromophenyl isobutyl sulfone; Benzene, 1-bromo-2-[(2-methylpropyl)sulfonyl]-; (2-Bromophenyl)(isobutyl)sulfone
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-(Isobutylsulfonyl)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to traceability and documentation supports cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.